Category: 2019 Research Awards

Inhibitors of pro-HGF activation overcome resistance to anti-EGFR therapy

September 16th, 2019 – Jim Janetka, PhD, Associate Professor of Biochemistry and Molecular Biophysics, and Co-Founder of ProteXase Therapeutics, Inc., along with Lidija Klampfer, PhD, Co-Founder and Chief Scientific Officer of ProteXase Therapeutics, Inc., received a one-year SBIR grant award from the National Cancer Institute for their research entitled “Inhibitors of pro-HGF activation overcome resistance to anti-EGFR therapy”.

Redefining Pediatric Dilated Cardiomyopathy through Precision Medicine

August 1st, 2019 – Together with Kory Lavine and Kathleen Simpson, the Greenberg lab received a Large Scale Interdisciplinary Research Initiative Grant from the Children’s Discovery Institute. The project, “Redefining Pediatric Dilated Cardiomyopathy through Precision Medicine” brings together a team of basic scientists and physician scientists to better understand pediatric heart failure and to develop novel therapeutics.

The role of pericellular serine proteases in tumor progression and resistance to anticancer therapy

June 14th, 2019 – Jim Janetka, PhD, Associate Professor of Biochemistry and Molecular Biophysics, received a two-year Siteman Investment Program (SIP) award from the Siteman Cancer Center and Foundation for Barnes Jewish-Hospital for his research entitled “The role of pericellular serine proteases in tumor progression and resistance to anticancer therapy”.

New chemical probes enable Mass Spectrometry-based footprinting of human protein structure in lipid membranes and cells

January 31st, 2019 – Weikai Li, PhD, assistant professor of biochemistry and molecular biophysics, along with Michael L. Gross, PhD, professor of chemistry, immunology, and medicine, received a new four year grant award from the National Institute of General Medical Sciences for their research entitled “New chemical probes enable Mass Spectrometry-based footprinting of human protein structure in lipid membranes and cells”.

Physics-based precision medicine: computationally phenotyping myosin isoforms and cardiomyopathy mutations

January 23rd, 2019 – Justin Porter, a Computational & Systems Biology student in the Bowman laboratory, received a three year National Research Service Award from the National Heart, Lung, and Blood Institute for his research entitled “Physics-based precision medicine: computationally phenotyping myosin isoforms and cardiomyopathy mutations”.