2016-02-26 – Rotation Talks:
Patrick Judge – Calculating Binding Energies and Distribution Coefficients with the AMOEBA Force Field
Cameron Sargent – Modifying the Target Specificity of VCre Recombinase for Recombination Mediated Cassette Exchange of the Huntington Locus
Reddy D.N., Ballante F., Chuang T., Pirolli A., Marrocco B., and Marshall G.R. (2016) “Design and Synthesis of Simplified Largazole Analogues as Isoform-Selective Human Lysine Deacetylase Inhibitors.” J Med Chem. 2016 Feb 25;59(4):1613-33. doi: 10.1021/acs.jmedchem.5b01632. Epub 2016 Jan 7. (Abstract)
February 20th, 2016 – Timothy M. Lohman, PhD, Marvin A. Brennecke Professor of Biophysics, department of biochemistry and molecular biophysics received a four year grant award from the National Institute of General Medical Sciences for his research entitled “SSB Protein/DNA Interactions”.
Burgers, P.M., Gordenin, D. and Kunkel, T.A.
Who Is Leading the Replication Fork, Pol ε or Pol δ?
Mol Cell. 61:492-493 (2016). (Abstract)
2016-02-12 – Jayan Rammohan (Galburt Lab) – Cooperative Stabilization of Mycobacterial Transcription Open-Complexes
2016-02-09 – David Piston – Quantitative Microscopy of Mechanisms Underlying Hormone Secretion
Elson E.L. & Genin G.M. (2016). “Tissue constructs: platforms for basic research and drug discovery.” Interface Focus. 2016 Feb 6;6(1):20150095. doi: 10.1098/rsfs.2015.0095. (Abstract)
Li Y., Huang G., Li M., Wang L., Elson E.L., Lu T.J., Genin G.M., & Xu F. (2016). “An approach to quantifying 3D responses of cells to extreme strain.” Sci Rep. 2016 Feb 18;6:19550. doi: 10.1038/srep19550. (Abstract)
Jarvis C., Han Z., Kalas V., Klein R., Pinkner J.S., Ford B., Binkley J., Cusumano C.K., Cusumano Z., Mydock-McGrane L., Hultren S.J., & Janetka J.W. (2016). “Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI.” ChemMedChem. 2016 Feb 17;11(4):367-73. doi: 10.1002/cmdc.201600006. Epub 2016 Jan 26. (Abstract)