Author: Conrad Weiland

Structural biases in disordered proteins are prevalent in the cell

David Moses, Karina Guadalupe, Feng Yu, Eduardo Flores, Anthony R Perez, Ralph McAnelly, Nora M Shamoon, Gagandeep Kaur, Estefania Cuevas-Zepeda, Andrea D Merg, Erik W Martin, Alex S Holehouse & Shahar Sukenik (2024). “Structural biases in disordered proteins are prevalent in the cell” Nat Struct Mol Biol. 2024 Feb;31(2):283-292. doi: 10.1038/s41594-023-01148-8. Epub 2024 Jan 4. (Abstract)

Dissecting the biophysics and biology of intrinsically disordered proteins

Priya R Banerjee, Alex S Holehouse, Richard Kriwacki, Paul Robustelli, Hao Jiang, Alexander I Sobolevsky, Jennifer M Hurley & Joshua T Mendell (2024). “Dissecting the biophysics and biology of intrinsically disordered proteins” Trends Biochem Sci. 2024 Feb;49(2):101-104. doi: 10.1016/j.tibs.2023.10.002. Epub 2023 Nov 8. (Abstract)

Insights into posttranslational regulation of skeletal muscle contractile function by the acetyltransferases, p300 and CBP

Gretchen A Meyer, Jeremie L A Ferey, James A Sanford, Liam S Fitzgerald, Akiva E Greenberg, Kristoffer Svensson, Michael J Greenberg & Simon Schenk (2024). “Insights into posttranslational regulation of skeletal muscle contractile function by the acetyltransferases, p300 and CBP” J Appl Physiol (1985). 2024 Jun 1;136(6):1559-1567. doi: 10.1152/japplphysiol.00156.2024. Epub 2024 May 9. (Abstract)

Dilated cardiomyopathy-associated skeletal muscle actin (ACTA1) mutation R256H disrupts actin structure and function and causes cardiomyocyte hypocontractility

Ankit Garg, Silvia Jansen, Rui Zhang, Kory J Lavine & Michael J Greenberg (2024). “Dilated cardiomyopathy-associated skeletal muscle actin (ACTA1) mutation R256H disrupts actin structure and function and causes cardiomyocyte hypocontractility” bioRxiv. [Preprint]. 2024 Mar 12:2024.03.10.583979. doi: 10.1101/2024.03.10.583979. (Abstract)

Loss of an extensive ciliary connectome induces proteostasis and cell fate switching in a severe motile ciliopathy

Steven L Brody, Jiehong Pan, Tao Huang, Jian Xu, Huihui Xu, Jeffrey Koenitizer, Steven K Brennan, Rashmi Nanjundappa, Thomas G Saba, Andrew Berical, Finn J Hawkins, Xiangli Wang, Rui Zhang, Moe R Mahjoub, Amjad Horani & Susan K Dutcher (2024). “Loss of an extensive ciliary connectome induces proteostasis and cell fate switching in a severe motile ciliopathy” bioRxiv. [Preprint]. 2024 Mar 21:2024.03.20.585965. doi: 10.1101/2024.03.20.585965. (Abstract)