Author: Conrad Weiland

Mastigoneme structure reveals insights into the O-linked glycosylation code of native hydroxyproline-rich helices

Jin Dai, Meisheng Ma, Qingwei Niu, Robyn J Eisert, Xiangli Wang, Poulomi Das, Karl F Lechtreck, Susan K Dutcher, Rui Zhang & Alan Brown (2024). “Mastigoneme structure reveals insights into the O-linked glycosylation code of native hydroxyproline-rich helices” Cell. 2024 Apr 11;187(8):1907-1921.e16. doi: 10.1016/j.cell.2024.03.005. Epub 2024 Mar 28. (Abstract)

Structural dynamics of the intrinsically disordered linker region of cardiac troponin T

Jasmine Cubuk, Lina Greenberg, Akiva E Greenberg, Ryan J Emenecker, Melissa D Stuchell-Brereton, Alex S Holehouse, Andrea Soranno & Michael J Greenberg (2024). “Structural dynamics of the intrinsically disordered linker region of cardiac troponin T” bioRxiv. [Preprint]. 2024 May 31:2024.05.30.596451. doi: 10.1101/2024.05.30.596451. (Abstract)

Structural basis of pH-dependent activation in a CLC transporter

Eva Fortea, Sangyun Lee, Rahul Chadda, Yiorgos Argyros, Priyanka Sandal, Robyn Mahoney-Kruszka, Hatice Didar Ciftci, Maria E Falzone, Gerard Huysmans, Janice L Robertson, Olga Boudker & Alessio Accardi (2024). “Structural basis of pH-dependent activation in a CLC transporter” Nat Struct Mol Biol. 2024 Apr;31(4):644-656. doi: 10.1038/s41594-023-01210-5. Epub 2024 Jan 26. (Abstract)

The disordered N-terminal tail of SARS-CoV-2 Nucleocapsid protein forms a dynamic complex with RNA

Jasmine Cubuk, Jhullian J Alston, J Jeremías Incicco, Alex S Holehouse, Kathleen B Hall, Melissa D Stuchell-Brereton & Andrea Soranno (2024). “The disordered N-terminal tail of SARS-CoV-2 Nucleocapsid protein forms a dynamic complex with RNA” Nucleic Acids Res. 2024 Mar 21;52(5):2609-2624. doi: 10.1093/nar/gkad1215. (Abstract)

A single-molecule method for measuring fluorophore labeling yields for the study of membrane protein oligomerization in membranes

Melanie Ernst, Tugba N Ozturk, Janice L Robertson (2023). “A single-molecule method for measuring fluorophore labeling yields for the study of membrane protein oligomerization in membranes” PLoS One. 2023 Jan 20;18(1):e0280693. doi: 10.1371/journal.pone.0280693. eCollection 2023. (Abstract)

A thermodynamic analysis of CLC transporter dimerization in lipid bilayers

Rahul Chadda, Taeho Lee, Robyn Mahoney-Kruszka, Elizabeth G Kelley, Nathan Bernhardt, Priyanka Sandal & Janice L Robertson (2023). “A thermodynamic analysis of CLC transporter dimerization in lipid bilayers” Proc Natl Acad Sci U S A. 2023 Oct 10;120(41):e2305100120. doi: 10.1073/pnas.2305100120. Epub 2023 Oct 3. (Abstract)

Extracellular domain mutations of the EGF receptor differentially modulate high-affinity and low-affinity responses to EGF receptor ligands

Jennifer L Macdonald-Obermann & Linda J Pike (2024). “Extracellular domain mutations of the EGF receptor differentially modulate high-affinity and low-affinity responses to EGF receptor ligands” J Biol Chem. 2024 Mar;300(3):105763. doi: 10.1016/j.jbc.2024.105763. Epub 2024 Feb 16. (Abstract)