Category: All Publications

TFIIH generates a six-base-pair open complex during RNAP II transcription initiation and start-site scanning.

Tomko E.J., Fishburn J., Hahn S., & Galburt E.A. (2017). “TFIIH generates a six-base-pair open complex during RNAP II transcription initiation and start-site scanning.” Nat Struct Mol Biol. 2017 Dec;24(12):1139-1145. doi: 10.1038/nsmb.3500. Epub 2017 Nov 6. (Abstract)

Endogenous retinoid X receptor ligands in mouse hematopoietic cells.

Niu H., Fujiwara H., di Martino O., Hadwiger G., Frederick T.E., Menéndez-Gutiérrez M.P., Ricote M., Bowman G.R., & Welch J.S. (2017). “Endogenous retinoid X receptor ligands in mouse hematopoietic cells.” Sci Signal. 2017 Oct 31;10(503). pii: eaan1011. doi: 10.1126/scisignal.aan1011. (Abstract)

Mechanistic Basis for ATP-Dependent Inhibition of Glutamine Synthetase by Tabtoxinine-β-lactam.

Patrick G.J., Fang L., Schaefer J., Singh S., Bowman G.R., & Wencewicz T.A. (2017). “Mechanistic Basis for ATP-Dependent Inhibition of Glutamine Synthetase by Tabtoxinine-β-lactam.” Biochemistry. 2018 Jan 9;57(1):117-135. doi: 10.1021/acs.biochem.7b00838. Epub 2017 Oct 31. (Abstract)

Characterization of histone acylations links chromatin modifications with metabolism

Johayra Simithy, Simone Sidoli, Zuo-Fei Yuan, Mariel Coradin, Natarajan V Bhanu, Dylan M Marchione, Brianna J Klein, Gleb A Bazilevsky, Cheryl E McCullough, Robert S Magin, Tatiana G Kutateladze, Nathaniel W Snyder, Ronen Marmorstein & Benjamin A Garcia (2017). “Characterization of histone acylations links chromatin modifications with metabolism” Nat Commun. 2017 Oct 26;8(1):1141. doi: 10.1038/s41467-017-01384-9. (Abstract)

Epidermal growth factor receptors containing a single tyrosine in their C-terminal tail bind different effector molecules and are signaling-competent.

Gill K., Macdonald-Obermann J.L., & Pike L.J. (2017). “Epidermal growth factor receptors containing a single tyrosine in their C-terminal tail bind different effector molecules and are signaling-competent.” J Biol Chem. 2017 Dec 15;292(50):20744-20755. doi: 10.1074/jbc.M117.802553. Epub 2017 Oct 26. (Abstract)

Combining short- and long-range fluorescence reporters with simulations to explore the intramolecular dynamics of an intrinsically disordered protein.

Zosel F., Haenni D., Soranno A., Nettels D., & Schuler B. (2017). “Combining short- and long-range fluorescence reporters with simulations to explore the intramolecular dynamics of an intrinsically disordered protein.” J Chem Phys. 2017 Oct 21;147(15):152708. doi: 10.1063/1.4992800. (Abstract)

Inhibition of calcium dependent protein kinase 1 (CDPK1) by pyrazolopyrimidine analogs decreases establishment and reoccurrence of central nervous system disease by Toxoplasma gondii.

Rutaganira F.U., Barks J., Dhason M.S., Wang Q., Lopez M.S., Long S., Radke J.B., Jones N.G., Maddirala A.R., Janetka J.W., El Bakkouri M., Hui R., Shokat K.M., & Sibley L.D. (2017). “Inhibition of calcium dependent protein kinase 1 (CDPK1) by pyrazolopyrimidine analogs decreases establishment and reoccurrence of central nervous system disease by Toxoplasma gondii.” J Med Chem. 2017 Dec 28;60(24):9976-9989. doi: 10.1021/acs.jmedchem.7b01192. Epub 2017 Oct 9. (Abstract)