Category: All Publications

Intrinsically disordered C-terminal tails of E. coli single-stranded DNA binding protein regulate cooperative binding to single-stranded DNA.

Kozlov A.G., Weiland E., Mittal A., Waldman V., Antony E., Fazio N., Pappu R.V., & Lohman T.M. (2015). “Intrinsically disordered C-terminal tails of E. coli single-stranded DNA binding protein regulate cooperative binding to single-stranded DNA.” J Mol Biol. 2015 Feb 27;427(4):763-74. doi: 10.1016/j.jmb.2014.12.020. Epub 2015 Jan 3. (Abstract)

A quantitative assay reveals ligand specificity of the DNA scaffold repair protein XRCC1 and efficient disassembly of complexes of XRCC1 and the poly(ADP-ribose) polymerase 1 by poly(ADP-ribose) glycohydrolase.

Kim I.K., Stegeman R.A., Brosey C.A., & Ellenberger T. (2015). “A quantitative assay reveals ligand specificity of the DNA scaffold repair protein XRCC1 and efficient disassembly of complexes of XRCC1 and the poly(ADP-ribose) polymerase 1 by poly(ADP-ribose) glycohydrolase.” J Biol Chem. 2015 Feb 6;290(6):3775-83. doi: 10.1074/jbc.M114.624718. Epub 2014 Dec 4. (Abstract)

Antibody mediated therapy targeting CD47 inhibits tumor progression of hepatocellular carcinoma.

Xiao Z.Y., Chung H., Banan B., Manning P.T., Ott K.C., Lin S., Capoccia B.J., Subramanian V., Hiebsch R.R., Upadhya G., Mohanakumar T., Frazier W.A., Lin Y., & Chapman W.C. (2015). “Antibody mediated therapy targeting CD47 inhibits tumor progression of hepatocellular carcinoma.” Cancer Lett. 2015 May 1;360(2):302-9. doi: 10.1016/j.canlet.2015.02.036. Epub 2015 Feb 23. (Abstract)

Thrombospondin-1 regulates bone homeostasis through effects on bone matrix integrity and nitric oxide signaling in osteoclasts.

Amend S.R., Uluckan O., Hurchla M., Leib D., Novack D.V., Silva M., Frazier W., & Weilbaecher K.N. (2015). “Thrombospondin-1 regulates bone homeostasis through effects on bone matrix integrity and nitric oxide signaling in osteoclasts.” J Bone Miner Res. 2015 Jan;30(1):106-15. doi: 10.1002/jbmr.2308. (Abstract)

CD47 blockade reduces ischemia/reperfusion injury and improves survival in a rat liver transplantation model.

Xiao Z.Y., Banan B., Jia J., Manning P.T., Hiebsch R.R., Gunasekaran M., Upadhya G., Frazier W.A., Mohanakumar T., & Chapman W.C. (2015). “CD47 blockade reduces ischemia/reperfusion injury and improves survival in a rat liver transplantation model.” Liver Transpl. 2015 Apr;21(4):468-477. doi: 10.1002/lt.24059. Epub 2015 Jan 29. (Abstract)