Category: All Publications

Mechanics of EGF receptor/ErbB2 kinase activation revealed by luciferase fragment complementation imaging.

Macdonald-Obermann J.L, Piwnica-Worms D., & Pike L.J. (2012). “Mechanics of EGF receptor/ErbB2 kinase activation revealed by luciferase fragment complementation imaging.” Proc Natl Acad Sci U S A. 2012 Jan 3;109(1):137-42. doi: 10.1073/pnas.1111316109. Epub 2011 Dec 21. (Abstract)

The membrane-proximal intracellular domain of the epidermal growth factor receptor underlies negative cooperativity in ligand binding.

Adak S., Yang K.S., Macdonald-Obermann J., & Pike L.J. (2011). “The membrane-proximal intracellular domain of the epidermal growth factor receptor underlies negative cooperativity in ligand binding.” J Biol Chem. 2011 Dec 30;286(52):45146-55. doi: 10.1074/jbc.M111.274175. Epub 2011 Nov 8. (Abstract)

Treatment and prevention of urinary tract infection with orally active FimH inhibitors.

Cusumano C.K., Pinkner J.S., Han Z., Greene S.E., Ford B.A., Crowley J.R., Henderson J.P., Janetka J.W., and Hultgren S.J.
Treatment and prevention of urinary tract infection with orally active FimH inhibitors.
Sci Transl Med. 3(109):109ra115. doi: 10.1126/scitranslmed.3003021. (2011) (Abstract)

Hydrogen/deuterium exchange and electron-transfer dissociation mass spectrometry determine the interface and dynamics of apolipoprotein E oligomerization.

Huang R.Y., Garai K., Frieden C., & Gross M.L. (2011). “Hydrogen/deuterium exchange and electron-transfer dissociation mass spectrometry determine the interface and dynamics of apolipoprotein E oligomerization.” Biochemistry. 2011 Nov 1;50(43):9273-82. doi: 10.1021/bi2010027. Epub 2011 Oct 5. (Abstract)