Adak S., Yang K.S., Macdonald-Obermann J., & Pike L.J. (2011). “The membrane-proximal intracellular domain of the epidermal growth factor receptor underlies negative cooperativity in ligand binding.” J Biol Chem. 2011 Dec 30;286(52):45146-55. doi: 10.1074/jbc.M111.274175. Epub 2011 Nov 8. (Abstract)
Adak S., Deandrade D., & Pike L.J. (2012). “The tethering arm of the EGF receptor is required for negative cooperativity and signal transduction.” J Biol Chem. 2011 Jan 14;286(2):1545-55. doi: 10.1074/jbc.M110.182899. Epub 2010 Nov 3. (Abstract)
Yang K.S., Macdonald-Obermann J., Piwnica-Worms D., & Pike L.J. (2010). “Asp-960/Glu-961 controls the movement of the C-terminal tail of the epidermal growth factor receptor to regulate asymmetric dimer formation.” J Biol Chem. 2010 Jul 30;285(31):24014-22. doi: 10.1074/jbc.M110.103317. Epub 2010 May 27. (Abstract)
Yang R.Y., Yang K.S., Pike L.J., and Marshall G.R. (2010) “Targeting the dimerization of epidermal growth factor receptors with small-molecule inhibitors.” Chem Biol Drug Des. 2010 Jul;76(1):1-9. doi: 10.1111/j.1747-0285.2010.00986.x. Epub 2010 May 4. (Abstract)
Macdonald-Obermann J.L. & Pike L.J. (2009). “The intracellular juxtamembrane domain of the epidermal growth factor (EGF) receptor is responsible for the allosteric regulation of EGF binding.” J Biol Chem. 2009 May 15;284(20):13570-6. doi: 10.1074/jbc.M109.001487. Epub 2009 Mar 31. (Abstract)
Pike L.J. (2009). “The challenge of lipid rafts.” J Lipid Res. 2009 Apr;50 Suppl:S323-8. doi: 10.1194/jlr.R800040-JLR200. Epub 2008 Oct 27. (Abstract)
Macdonald-Obermann J.L. & Pike L.J. (2009). “Palmitoylation of the EGF receptor impairs signal transduction and abolishes high-affinity ligand binding.” Biochemistry. 2009 Mar 24;48(11):2505-13. doi: 10.1021/bi802249x. (Abstract)
Yang K.S., Ilagan M.X., Pinica-Worms D. and Pike L.J. (2009) “Luciferase fragment complementation imaging of conformational changes in the epidermal growth factor receptor.” J Biol Chem. 2009 Mar 20;284(12):7474-82. doi: 10.1074/jbc.M808041200. Epub 2009 Jan 26. (Abstract)
Eiblmaier M., Meyer L.A., Watson M.A., Fracasso P.M., Pike L.J. & Anderson C.J. (2008). “Correlating EGFR expression with receptor-binding properties and internalization of 64Cu-DOTA-cetuximab in 5 cervical cancer cell lines.” J Nucl Med. 2008 Sep;49(9):1472-9. doi: 10.2967/jnumed.108.052316. Epub 2008 Aug 14. (Abstract)
Macdonald J.L. & Pike L.J. (2008). “Heterogeneity in EGF-binding affinities arises from negative cooperativity in an aggregating system.” Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):112-7. doi: 10.1073/pnas.0707080105. Epub 2007 Dec 28. (Abstract)