Category: Pike Publications

Asp-960/Glu-961 controls the movement of the C-terminal tail of the epidermal growth factor receptor to regulate asymmetric dimer formation.

Yang K.S., Macdonald-Obermann J., Piwnica-Worms D., & Pike L.J. (2010). “Asp-960/Glu-961 controls the movement of the C-terminal tail of the epidermal growth factor receptor to regulate asymmetric dimer formation.” J Biol Chem. 2010 Jul 30;285(31):24014-22. doi: 10.1074/jbc.M110.103317. Epub 2010 May 27. (Abstract)

Targeting the dimerization of epidermal growth factor receptors with small-molecule inhibitors.

Yang R.Y., Yang K.S., Pike L.J., and Marshall G.R. (2010) “Targeting the dimerization of epidermal growth factor receptors with small-molecule inhibitors.” Chem Biol Drug Des. 2010 Jul;76(1):1-9. doi: 10.1111/j.1747-0285.2010.00986.x. Epub 2010 May 4. (Abstract)

The intracellular juxtamembrane domain of the epidermal growth factor (EGF) receptor is responsible for the allosteric regulation of EGF binding.

Macdonald-Obermann J.L. & Pike L.J. (2009). “The intracellular juxtamembrane domain of the epidermal growth factor (EGF) receptor is responsible for the allosteric regulation of EGF binding.” J Biol Chem. 2009 May 15;284(20):13570-6. doi: 10.1074/jbc.M109.001487. Epub 2009 Mar 31. (Abstract)

Luciferase fragment complementation imaging of conformational changes in the epidermal growth factor receptor.

Yang K.S., Ilagan M.X., Pinica-Worms D. and Pike L.J. (2009) “Luciferase fragment complementation imaging of conformational changes in the epidermal growth factor receptor.” J Biol Chem. 2009 Mar 20;284(12):7474-82. doi: 10.1074/jbc.M808041200. Epub 2009 Jan 26. (Abstract)

Correlating EGFR expression with receptor-binding properties and internalization of 64Cu-DOTA-cetuximab in 5 cervical cancer cell lines.

Eiblmaier M., Meyer L.A., Watson M.A., Fracasso P.M., Pike L.J. & Anderson C.J. (2008). “Correlating EGFR expression with receptor-binding properties and internalization of 64Cu-DOTA-cetuximab in 5 cervical cancer cell lines.” J Nucl Med. 2008 Sep;49(9):1472-9. doi: 10.2967/jnumed.108.052316. Epub 2008 Aug 14. (Abstract)