December 15th, 2020 – Michael S Kinch, Ph.D., Associate Vice Chancellor, Director, Centers for Research Innovation in Biotechnology & Drug Discovery, and Professor of Biochemistry and Molecular Biophysics, received a new one-year grant award from Arnold Ventures for his research entitled “CDEK: Clinical Data Experience Knowledge-base”.
Miao Gui, Meisheng Ma, Erica Sze-Tu, Xiangli Wang, Fujiet Koh, Ellen D. Zhong, Bonnie Berger, Joseph H. Davis, Susan K. Dutcher, Rui Zhang, & Alan Brown (2020). “Structures of radial spokes and associated complexes important for ciliary motility” Nat Struct Mol Biol. 2021 Jan;28(1):29-37. doi: 10.1038/s41594-020-00530-0. Epub 2020 Dec 14. (Abstract)
2020-12-08 – Lillian Chong, Ph.D. – University of Pittsburgh – “The Art of Possibility: Weighted Ensemble Simulations of Long-timescale Kinetics.” (more…)
2020-12-01 – Danuta Szczesna-Cordary, Ph.D. – University of Miami, Miller School of Medicine – “Genetic cardiomyopathies associated with mutations in myosin light chains: underlying mechanisms and potential treatments” (more…)
Meghana Kshirsagar, Nure Tasnina, Michael D. Ward, Jeffrey N. Law, T. M. Murali, Juan M. Lavista Ferres, Gregory R. Bowman, & Judith Klein-Seetharaman (2020). “Protein sequence models for prediction and comparative analysis of the SARS-CoV-2 -human interactome” Pac Symp Biocomput. 2021;26:154-165. (Abstract)
2020-11-24 – Magnus Kjærgaard, Ph.D. – Aarhus University in Denmark – “Intrinsically disordered linkers are regulators of kinase signaling and protein interactions” (more…)
Mr. Matthew A. Cruz joined the lab of Dr. Gregory Bowman in the department of Biochemistry and Molecular Biophysics where he studies the relationship between an ebolavirus protein’s structural dynamics and its function. Through computational and experimental techniques he is measuring how changes in protein dynamics affect RNA binding. Matthew is applying this research to find drugs that disrupt protein dynamics to combat ebolavirus infections. (more…)
Melanie A. Sparks, Peter M. Burgers, & Roberto Galletto (2020). “Pif1, RPA and FEN1 modulate the ability of DNA polymerase δ to overcome protein barriers during DNA synthesis” J Biol Chem. 2020 Nov 20;295(47):15883-15891. doi: 10.1074/jbc.RA120.015699. Epub 2020 Sep 10. (Abstract)
Work by Dr. Burgers on cancer research has been featured in Nature Structural & Molecular Biology.
You can view the article by clicking here: Making cancer cells more susceptible to dying
2020-11-17 – Simon Scheuring, Ph.D. – Weill Cornell Medicine – “High-Speed Atomic Force Microscopy: A forceful Tool for Molecular Biophysics” (more…)