Biography:
Emma received her B.S. in Biochemistry and her B.A. in Microbiology from Indiana University in Bloomington. After graduation, Emma joined the Medical Scientist Training Program at Washington University in St. Louis where she became part of the Immunology program in the Division of Biology and Biomedical Sciences for her graduate studies. (more…)
Biography:
Sarah received her undergraduate degree in biochemistry from the Ohio State University and joined the Division of Biological and Biomedical Sciences at Washington University in St. Louis in 2016 as part of the Biochemistry, Biophysics, and Structural Biology. Sarah is completing her thesis work in the lab of Dr. Michael Greenberg with her focus being the study of mutations in the protein troponin T which lead to familial cardiomyopathies. (more…)
January 11th, 2021 – Alex Holehouse, Ph.D., Assistant Professor of Biochemistry and Molecular Biophysics, received a new one year grant award from Dewpoint Therapeutics for his research entitled “Bioinformatic tools for the analysis of phase separating proteins”.
Michael D. Onken, Kendall J. Blumer, & John A. Cooper (2021). “Uveal melanoma cells use ameboid and mesenchymal mechanisms of cell motility crossing the endothelium” Mol Biol Cell. 2021 Jan 6;mbcE20040241. doi: 10.1091/mbc.E20-04-0241. Online ahead of print. (Abstract)
Thomas Blackwell, W. Tom Stump, Sarah R. Clippinger, & Michael J. Greenberg (2021). “Computational Tool for Ensemble Averaging of Single-Molecule Data” Biophys J. 2021 Jan 5;120(1):10-20. doi: 10.1016/j.bpj.2020.10.047. Epub 2020 Nov 26. (Abstract)
Tom Rapoport, PhD, from Harvard Medical School, presented the 2020 Carl and Gerty Cori Lecture on November 12, 2020, via Zoom.
Dr. Rapoport’s seminar was entitled “Mechanism of ER-Associated Protein Degradation (“ERAD”)”.
For more information on Dr. Tom Rapoport, please click here.
To see a recording of Dr. Rapoport’s lecture, please click here.
Shixuan Liu, Shuang Li, Guomin Shen, Narayanasami Sukumar, Andrzej M. Krezel, & Weikai Li (2021). “Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation” Science. 2021 Jan 1;371(6524):eabc5667. doi: 10.1126/science.abc5667. Epub 2020 Nov 5. (Abstract)
Dr. Linda Kurz, emeritus research faculty member of our department, died on December 17, 2020, at home in rural Franklin County. She was 74.
Dr. Kurz worked with Drs. Carl Frieden and George Drysdale for many years, investigating enzyme mechanisms. She was true biochemist, as hard-core as they come. She retired a few years ago, and many of us overlapped with her for a substantial period of time. I believe she gets credit for the sign on the Frieden lab door saying “if we knew what we were doing, it wouldn’t be research.”
To read more, including remembrances from colleagues click here.
Vishnu C. Damalanka, Amarendar Reddy Maddirala, & James W. Janetka (2020). “Novel approaches to glycomimetic design: Development of small molecular weight lectin antagonists” Expert Opin Drug Discov. 2020 Dec 18. doi: 10.1080/17460441.2021.1857721. Online ahead of print. (Abstract)
Jesse G. Meyer, Natalie M. Niemi, David J. Pagliarini, & Joshua J. Coon (2020). “Quantitative shotgun proteome analysis by direct infusion” Nat Methods. 2020 Dec;17(12):1222-1228. doi: 10.1038/s41592-020-00999-z. Epub 2020 Nov 23. (Abstract)