Author: Nicholas Caito

Inhibitors of growth factor activation as new adjunct chemotherapy for cancer

September 27th, 2016 – Jim Janetka, PhD, Associate Professor, Department of Biochemistry and Molecular Biophysics, received a new two year grant award from the Alvin J. Siteman Cancer Research Fund for his research entitled “Inhibitors of growth factor activation as new adjunct chemotherapy for cancer”.

More information here: “Siteman fund grants $300,000 for unique approaches to fighting cancer

RNF4-Dependent Oncogene Activation by Protein Stabilization.

Thomas J.J., Abed M., Heuberger J., Novak R., Zohar Y., Beltran Lopez A.P., Trausch-Azar J.S., Ilagan M.X., Benhamou D., Dittmar G., Kopan R., Birchmeier W., Schwartz A.L., and Orian A. (2016) “RNF4-Dependent Oncogene Activation by Protein Stabilization.” Cell Rep. 2016 Sep 20;16(12):3388-3400. doi: 10.1016/j.celrep.2016.08.024. (Abstract)

Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration.

Xu X., Wang X., Todd E.M., Jaeger E.R., Vella J.L., Mooren O.L., Feng Y., Hu J., Cooper J.A., Morley S.C., & Huang Y.H. (2016). “Mst1 Kinase Regulates the Actin-Bundling Protein L-Plastin To Promote T Cell Migration.” J Immunol. 2016 Sep 1;197(5):1683-91. doi: 10.4049/jimmunol.1600874. Epub 2016 Jul 27. (Abstract)

Consistent View of Polypeptide Chain Expansion in Chemical Denaturants from Multiple Experimental Methods.

Borgia A., Zheng W., Buholzer K., Borgia M.B., Schüler A., Hofmann H., Soranno A., Nettels D., Gast K., Grishaev A., Best R.B., & Schuler B. (2016). “Consistent View of Polypeptide Chain Expansion in Chemical Denaturants from Multiple Experimental Methods.” J Am Chem Soc. 2016 Sep 14;138(36):11714-26. doi: 10.1021/jacs.6b05917. Epub 2016 Sep 1. (Abstract)

Congratulations to Sarem Hailemariam for being selected for the 2016 MilliporeSigma Fellowship in memory of Dr. Gerty Cori

Ms. Hailemariam received her undergraduate degree in Biology from Shaw University in Raleigh, North Carolina. She joined the Division of Biological and Biomedical Sciences at Washington University in St. Louis in 2012 as part of the Molecular Cell Biology program. (more…)

2016 Joint Department Welcome BBQ

On August 25, 2016, the Biochemistry Department and the Graduate Programs in Biochemistry and Computational & Molecular Biophysics hosted a welcome BBQ for the new incoming students.
The BBQ was held in Forest Park with food catered from Vernon’s BBQ. (Photos)