Author: Nicholas Caito

Solution NMR structure of CsgE: Structural insights into a chaperone and regulator protein important for functional amyloid formation.

Shu Q., Krezel A.M., Cusumano Z.T., Pinkner J.S., Klein R., Hultgren S.J., & Frieden C. (2016). “Solution NMR structure of CsgE: Structural insights into a chaperone and regulator protein important for functional amyloid formation.” Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7130-5. doi: 10.1073/pnas.1607222113. Epub 2016 Jun 13. (Abstract)

Cooperative stabilization of Mycobacterium tuberculosis rrnAP3 promoter open complexes by RbpA and CarD.

Rammohan J., Ruiz Manzano A., Garner A.L., Prusa J. Stallings C.L., & Galburt E.A. (2016). “Cooperative stabilization of Mycobacterium tuberculosis rrnAP3 promoter open complexes by RbpA and CarD.” Nucleic Acids Res. 2016 Sep 6;44(15):7304-13. doi: 10.1093/nar/gkw577. Epub 2016 Jun 24. (Abstract)

Dr. Thomas Kraft Selected to Receive the 2016 Ceil M. DeGutis Prize

Thomas KraftOn June 21, 2016, Dr. Thomas Kraft was selected to receive the 2016 Ceil M. DeGutis Prize in Chemical Biology/Medicinal Chemistry. This award was given in recognition of Dr. Kraft’s significant contribution to the field of Chemical Biology/Medicinal Chemistry.

Dr. Kraft was nominated by his mentor Dr. Paul Hruz for the research that Dr. Kraft did to develop novel tools to investigate the structure and function of the insulin-responsive facilitative glucose transporter GLUT4.

Dr. Thomas Kraft was a DBBS student in the Biochemistry program. After his defense, Dr. Kraft did a very short postdoc in the laboratory of Dr. Xander Barnes in the Department of Chemistry at Washington University. In June, Dr. Kraft accepted a postdoctoral position at Roche Pharma Research and Early Development, Roche Innovation Center in Penzberg, Germany.

Transcription Start Site Scanning and the Requirement for ATP during Transcription Initiation by RNA Polymerase II.

Fishburn J., Galburt E., & Hahn S. (2016). “Transcription Start Site Scanning and the Requirement for ATP during Transcription Initiation by RNA Polymerase II.” J Biol Chem. 2016 Jun 17;291(25):13040-7. doi: 10.1074/jbc.M116.724583. Epub 2016 Apr 17. (Abstract)

Remodeling by fibroblasts alters the rate-dependent mechanical properties of collagen.

Babaei B., Davarian A., Lee S.L., Pryse K.M., McConnaughey W.B., Elson E.L., & Genin G.M. (2016). “Remodeling by fibroblasts alters the rate-dependent mechanical properties of collagen.” Acta Biomater. 2016 Jun;37:28-37. doi: 10.1016/j.actbio.2016.03.034. Epub 2016 Mar 23. (Abstract)