Department of Biochemistry and Molecular Biophysics

Author: RCG Admin

2017 News / All News

Congratulations to Arthur Sletton for receiving the 2017 David F. Silbert Outstanding Teaching Assistant Award.

The 2016-2017 David F. Silbert Outstanding Teaching Assistant Award foes to Mr. Arthur Sletton for his work in the 2016 Fall Human Body course. Mr. Sletton was nominated by Drs. Kari Allen, Glenn Conroy and Jane Phillips-Conroy. Mr. Sletton exemplified the spirit of this award through his dedication and lasting contribution to the course, the course instructors, and the students in the class. (more…)

All Publications / Li Publications

Membrane Protein Structure in Live Cells: Methodology for Studying Drug Interaction by Mass Spectrometry-Based Footprinting.

Shen G., Li S., Cui W., Liu S., Yang Y., Gross M., & Li W. (2017). “Membrane Protein Structure in Live Cells: Methodology for Studying Drug Interaction by Mass Spectrometry-Based Footprinting.” Biochemistry. 2018 Jan 23;57(3):286-294. doi: 10.1021/acs.biochem.7b00874. Epub 2017 Dec 20. (Abstract)

All Publications / Janetka Publications

Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.

Spaulding C.N., Klein R.D., Ruer S., Kau A.L., Schreiber H.L., Cusumano Z.T., Dodson K.W., Pinkner J.S., Fremont D.H., Janetka J.W., Remaut H., Gordon J.I., & Hultgren S.J. (2017). “Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.” Nature. 2017 Jun 22;546(7659):528-532. doi: 10.1038/nature22972. Epub 2017 Jun 14. (Abstract)

All Publications / Cooper Publications / Onken Publications

Technical Advance: New in vitro method for assaying the migration of primary B cells using an endothelial monolayer as substrate.

Stewart-Hutchinson P.J., Szasz T.P., Jaeger E.R., Onken M.D., Cooper J.A., & Morley S.C. (2017). “Technical Advance: New in vitro method for assaying the migration of primary B cells using an endothelial monolayer as substrate.” J Leukoc Biol. 2017 Sep;102(3):941-948. doi: 10.1189/jlb.1TA0117-008R. Epub 2017 Jun 21. (Abstract)

2017 News / All News

Jim Janetka’s work featured in The Source

Congratulations to Jim Janetka, whose work on UTI treatments was featured in The Source.

Dr. Janetka helped with a new study that may prevent the common problem of recurrent urinary tract infections with the use of a molecular decoy that targets e. coli bacteria.

You can read more about the work in the The Source by clicking HERE or on the picture of e. coli.

2017 Events / All Events

Pedal the Cause – Happy Hour Fundraiser

Please join us for a Happy Hour at itap in the Central West End to raise money for cancer research! Sixty percent of sales of the designated beer will be donated (beer TBA). Feel free to stay around after Happy Hour for itap’s weekly trivia night too!

The event will be on Thursday, June 15th, from 4 PM to 7 PM.

More information and links can be found on HERE.

All Publications / Janetka Publications

Targeting the tumor-promoting microenvironment in MET-amplified NSCLC cells with a novel inhibitor of pro-HGF activation.

Owusu B.Y., Thomas S., Venukadasula P., Han Z., Janetka J.W., Galemmo R.A. Jr., & Klampfer L. (2017). “Targeting the tumor-promoting microenvironment in MET-amplified NSCLC cells with a novel inhibitor of pro-HGF activation.” Oncotarget. 2017 May 29;8(38):63014-63025. doi: 10.18632/oncotarget.18260. eCollection 2017 Sep 8. (Abstract)

All Publications / Marshall Publications

Design and synthesis of benzodiazepine analogs as isoform-selective human lysine deacetylase inhibitors.

Reddy D.R., Ballante F., Zhou N.J., and Marshall G.R. (2017) “Design and synthesis of benzodiazepine analogs as isoform-selective human lysine deacetylase inhibitors.” Eur J Med Chem. 2017 Feb 15;127:531-553. doi: 10.1016/j.ejmech.2016.12.032. Epub 2016 Dec 18. (Abstract)