Department of Biochemistry and Molecular Biophysics

Category: All Publications

All Publications / Holehouse Publications

Arginine-Enriched Mixed-Charge Domains Provide Cohesion for Nuclear Speckle Condensation.

Greig J.A., Nguyen T.A., Lee M., Holehouse A.S., Posey A.E., Pappu R.V., & Jedd G. (2020). “Arginine-Enriched Mixed-Charge Domains Provide Cohesion for Nuclear Speckle Condensation.” Mol Cell. 2020 Feb 6. pii: S1097-2765(20)30046-0. doi: 10.1016/j.molcel.2020.01.025. [Epub ahead of print] (Abstract)

All Publications / Janetka Publications

Heteroarylamide smoothened inhibitors: Discovery of N-[2,4-dimethyl-5-(1-methylimidazol-4-yl)phenyl]-4-(2-pyridylmethoxy)benzamide (AZD8542) and N-[5-(1H-imidazol-2-yl)-2,4-dimethyl-phenyl]-4-(2- pyridylmethoxy)benzamide (AZD7254).

Yang B., Hird A.W., Bodnarchuk M.S., Zheng X., Dakin L., Su Q., Daly K., Godin R., Hattersley M.M., Brassil P., Redmond S., John Russell D., & Janetka J.W. (2020). “Heteroarylamide smoothened inhibitors: Discovery of N-[2,4-dimethyl-5-(1-methylimidazol-4-yl)phenyl]-4-(2-pyridylmethoxy)benzamide (AZD8542) and N-[5-(1H-imidazol-2-yl)-2,4-dimethyl-phenyl]-4-(2- pyridylmethoxy)benzamide (AZD7254).” Bioorg Med Chem. 2020 Jan 15;28(2):115227. doi: 10.1016/j.bmc.2019.115227. Epub 2019 Dec 11. (Abstract)

All Publications / Li Publications

The Tetraspanin CD53 Regulates Early B Cell Development by Promoting IL-7R Signaling.

Zev J. Greenberg, Darlene A. Monlish, Rachel L. Bartnett, Yihu Yang, Guomin Shen, Weikai Li, Jeffrey J. Bednarski, & Laura G. Schuettpelz. (2020). “The Tetraspanin CD53 Regulates Early B Cell Development by Promoting IL-7R Signaling.” J Immunol. 2020 Jan 1;204(1):58-67. doi: 10.4049/jimmunol.1900539. Epub 2019 Nov 20. (Abstract)

All Publications / Hall Publications

Ribosomal Protein L11 Selectively Stabilizes a Tertiary Structure of the GTPase Center rRNA Domain.

Welty R., Rau M., Pabit S., Dunstan M.S., Conn G.L., Pollack L., & Hall K.B. (2019). “Ribosomal Protein L11 Selectively Stabilizes a Tertiary Structure of the GTPase Center rRNA Domain.” J Mol Biol. 2019 Dec 24. pii: S0022-2836(19)30710-7. doi: 10.1016/j.jmb.2019.12.010. [Epub ahead of print] (Abstract)

All Publications / Ilagan Publications

The Aminoalkylindole BML-190 Negatively Regulates Chitosan Synthesis via the Cyclic AMP/Protein Kinase A1 Pathway in Cryptococcus neoformans.

Maybruck B.T., Lam W.C., Specht C.A., Ilagan M.X.G., Donlin M.J., & Lodge J.K. (2019). “The Aminoalkylindole BML-190 Negatively Regulates Chitosan Synthesis via the Cyclic AMP/Protein Kinase A1 Pathway in Cryptococcus neoformans.” mBio. 2019 Dec 17;10(6). pii: e02264-19. doi: 10.1128/mBio.02264-19. (Abstract)

All Publications / Greenberg, M. Publications

The Mutation R94C InTNNT2-encoded Troponin T Predisposes to Restrictive Cardiomyopathy and Pediatric Sudden Death Through Impaired Thin Filament Relaxation Resulting in Myocardial Diastolic Dysfunction

Jordan E Ezekian, Sarah R Clippinger, Jackie Garcia, Susan W Denfield, Aamir Jeewa, William Dreyer, Wenxin Zou, Yuxin Fan, Hugh D Allen, Jeffrey Kim, Michael Greenberg, & Andrew P Landstrom (2019). “The Mutation R94C InTNNT2-encoded Troponin T Predisposes to Restrictive Cardiomyopathy and Pediatric Sudden Death Through Impaired Thin Filament Relaxation Resulting in Myocardial Diastolic Dysfunction” American Heart Association, Inc. 11 Nov 2019, Circulation. 2019;140:A12139 (Abstract)

All Publications / Burgers Publications

Cryo-EM Structure of Nucleotide-Bound Tel1ATM Unravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations.

Yates L.A., Williams R.M., Hailemariam S., Ayala R., Burgers P., & Zhang X. (2019). “Cryo-EM Structure of Nucleotide-Bound Tel1ATM Unravels the Molecular Basis of Inhibition and Structural Rationale for Disease-Associated Mutations.” Structure. 2019 Nov 4. pii: S0969-2126(19)30353-3. doi: 10.1016/j.str.2019.10.012. [Epub ahead of print] (Abstract)