Ishan Taneja & Alex S. Holehouse (2021). “Folded domain charge properties influence the conformational behavior of disordered tails” Curr Res Struct Biol. 2021 Sep 7;3:216-228. doi: 10.1016/j.crstbi.2021.08.002. eCollection 2021. (Abstract)
Linxuan Hao, Rui Zhang, & Timothy M. Lohman (2021). “Heterogeneity in E. coli RecBCD Helicase-DNA Binding and Base Pair Melting” J Mol Biol. 2021 Sep 3;433(18):167147. doi: 10.1016/j.jmb.2021.167147. Epub 2021 Jul 9. (Abstract)
Maria Papadaki, Theerachat Kampaengsri, Samantha K. Barrick, Stuart G. Campbell, Dirk von Lewinski, Peter P. Rainer, Samantha P. Harris, Michael J. Greenberg, & Jonathan A. Kirk (2021). “Myofilament glycation in diabetes reduces contractility by inhibiting tropomyosin movement, is rescued by cMyBPC domains” J Mol Cell Cardiol. 2021 Sep 3;162:1-9. doi: 10.1016/j.yjmcc.2021.08.012. Online ahead of print. (Abstract)
Ryan J. Emenecker, Daniel Griffith, & Alex S. Holehouse (2021). “Metapredict: a fast, accurate, and easy-to-use predictor of consensus disorder and structure” Biophys J. 2021 Sep 2;S0006-3495(21)00725-6. doi: 10.1016/j.bpj.2021.08.039. Online ahead of print. (Abstract)
August 24th, 2021 – Benjamin Garcia, PhD, Raymond H. Wittcoff Distinguished Professor and Head of Biochemistry and Molecular Biophysics, along with Matthew D. Weitzman, PhD, Professor of Microbiology, Professor of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine and Children’s Hospital of Philadelphia, received a five year grant renewal from the National Institute of Allergy and Infectious Diseases for their research entitled “Viral modulation of epitranscriptomic mechanisms”.
Fengbo Zhou, Yihu Yang, Saketh Chemuru, Weidong Cui, Shixuan Liu, Michael Gross, & Weikai Li (2021). “Footprinting Mass Spectrometry of Membrane Proteins: Ferroportin Reconstituted in Saposin A Picodiscs” Anal Chem. 2021 Aug 24;93(33):11370-11378. doi: 10.1021/acs.analchem.1c02325. Epub 2021 Aug 12. (Abstract)
August 23rd, 2021 – Jhullian Jamille Alston, BA, Pre-Doc Trainee in the department of Biochemistry and Molecular Biophysics, and the laboratories of Alex Holehouse, PhD and Andrea Soranno, PhD, received a Predoctoral to Postdoctoral Fellow Transition Award from the National Cancer Institute for his research entitled “Single Molecule Biophysics of Intrinsically Disordered Proteins in Disease”.
August 18th, 2021 – Alex Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics, along with Shahar Sukenik, Assistant Professor, Department of Chemistry & Biochemistry at University of California, Merced, and Thomas Boothby, Assistant Professor, Department of Molecular Biology, University of Wyoming, received a new four year grant award from the National Science Foundation through the new “Integrative Research in Biology” mechanism for their research entitled “Collaborative Research: Functional Synergy Between Disordered Proteins and their Environment in Desiccation Protection”.
August 17th, 2021 – Matthew A Cruz, BS, Pre-Doc Trainee in the department of Biochemistry and Molecular Biophysics, and the laboratory of Gregory Bowman, PhD, received a new three-year fellowship award from the National Institutes of Health, National Institute of Allergy and Infectious Diseases for his research entitled “Leveraging protein dynamics to drug filovirus protein-nucleic acid interactions using simulations and experiments”.
August 17th, 2021 – Andrea Soranno, PhD, Assistant Professor of Biochemistry and Molecular Biophysics, Carl Frieden, PhD, Professor of Biochemistry and Molecular Biophysics, and Rui Zhang, PhD, Assistant Professor of Biochemistry and Molecular Biophysics will collaborate in the Project named “ApoE isoform-specific structure: insights on biology and pathobiology”. The Project is part of the newly awarded five-year U19 Research Program from the National Institutes of Health, National Institute of Aging, entitled “Biology and pathobiology of apoE in aging and Alzheimer’s disease”, helmed by Dr. David Holtzman, Professor and Chair of the Department of Neurology at Washington University, in St Louis, and Dr. Guojun Bu, Professor of Medicine and Chair of the Department of Neuroscience, Mayo Clinic.