April 23rd 2021 – Tugba Ozturk
2021-04-23 – Tugba Ozturk (Robertson Lab) – How do tryptophans modulate protein association in membranes?
Author: Nicholas Caito
Probing E. coli SSB Protein-DNA topology by reversing DNA backbone polarity
Alexander G. Kozlov & Timothy M. Lohman (2021). “Probing E. coli SSB Protein-DNA topology by reversing DNA backbone polarity” Biophys J. 2021 Apr 20;120(8):1522-1533. doi: 10.1016/j.bpj.2021.02.025. Epub 2021 Feb 23. (Abstract)
The importance of protein dynamics for kinase activation and inhibitor design: the case of ERK2
2021-04-20 – Dr. Natalie Ahn – The importance of protein dynamics for kinase activation and inhibitor design: The case of ERK2 (more…)
Intrinsic Disorder and Agonist Bias in EGF Receptor Signaling
April 15th, 2021 – Linda J. Pike, PhD, Professor of Biochemistry and Molecular Biophysics, along with Alexander S. Holehouse, PhD, Assistant Professor of Biochemistry and Molecular Biophysics, and Gary J. Patti, PhD, Professor of Chemistry and of Genetics and Medicine, received a new four year grant award from the National Institute of General Medical Sciences for their research entitled “Intrinsic Disorder and Agonist Bias in EGF Receptor Signaling”.
How to Build an Action Potential: Coordinated Biosynthesis of Multiple Ion Channel Types
2021-04-13 – Gail Robertson, Ph.D. – University of Wisconsin-Madison – “How to Build an Action Potential: Coordinated Biosynthesis of Multiple Ion Channel Types” (more…)
Membrane transporter dimerization driven by differential lipid solvation energetics of dissociated and associated states
Rahul Chadda, Nathan Bernhardt, Elizabeth G. Kelley, Susana Cm. Teixeira, Kacie Griffith, Alejandro Gil-Ley, Tuğba N. Öztürk, Lauren E. Hughes, Ana Forsythe, Venkatramanan Krishnamani, José D. Faraldo-Gómez, & Janice L. Robertson (2021). “Membrane transporter dimerization driven by differential lipid solvation energetics of dissociated and associated states” Elife. 2021 Apr 7;10:e63288. doi: 10.7554/eLife.63288. (Abstract)
Phosphorylation tunes tau’s effects on intracellular transport
2021-04-06 – Adam Hendricks, Ph.D. – McGill University – “Phosphorylation tunes tau’s effects on intracellular
transport” (more…)
Lessons learned from studying pathogenic variants in cardiac thin filament proteins
2021-03-30 – Jose Pinto, Ph.D. – Florida State University – “Lessons learned from studying pathogenic variants in cardiac thin filament proteins” (more…)
The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA
Jasmine Cubuk, Jhullian J. Alston, J. Jeremías Incicco, Sukrit Singh, Melissa D. Stuchell-Brereton, Michael D. Ward, Maxwell I. Zimmerman, Neha Vithani, Daniel Griffith, Jason A. Wagoner, Gregory R. Bowman, Kathleen B. Hall, Andrea Soranno, & Alex S. Holehouse. (2021). “The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA” Nat Commun. 2021 Mar 29;12(1):1936. doi: 10.1038/s41467-021-21953-3. (Abstract)
The Context-Dependent Influence of Promoter Sequence Motifs on Transcription Initiation Kinetics and Regulation
Drake Jensen & Eric A. Galburt (2021). “The Context-Dependent Influence of Promoter Sequence Motifs on Transcription Initiation Kinetics and Regulation” J Bacteriol. 2021 Mar 23;203(8):e00512-20. doi: 10.1128/JB.00512-20. Print 2021 Mar 23. (Abstract)