Department of Biochemistry and Molecular Biophysics

Author: Nicholas Caito

All Publications / Janetka Publications

A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis

Lisa K. McLellan, Michael R. McAllaster, Arthur S. Kim, Ľubomíra Tóthová, Patrick D. Olson, Jerome S. Pinkner, Allyssa L. Daugherty, Teri N. Hreha, James W. Janetka, Daved H. Fremont, Scott J. Hultgren, Herbert W. Virgin, & David A Hunstad (2021). “A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis” PLoS Pathog. 2021 Jan 29;17(1):e1009314. doi: 10.1371/journal.ppat.1009314. eCollection 2021 Jan. (Abstract)

2021 Events / All Events

Career Panel Discussion – 2021

On January 22nd, 2021, the department hosted a Career Panel Discussion on how to apply for jobs in academia and industry. Panelist included: Dr. Erin Heckler, Director, Office of Postdoctoral Affairs; Dr. Alex Holehouse, Assistant Professor, Biochemistry and Molecular Biophysics; Dr. Ron Dolle, Chemistry Director, Center for Drug Discovery; Dr. Michael Kinch, Director, Center for Drug Discovery.

If you would like to view this panel discussion, please click here.

2021 Research Awards / Li / Research Awards

Interdisciplinary structural studies of iron homeostasis in cardiovascular health

January 22nd, 2021 – Weikai Li, PhD, Associate Professor of Biochemistry and Molecular Biophysics, along with Michael L. Gross, PhD, Professor of Chemistry, Immunology, and Medicine, and Michael J. Greenberg, PhD, Assistant Professor of Biochemistry and Molecular Biophysics, received a new three-year grant award from American Heart Association for their research entitled “Interdisciplinary structural studies of iron homeostasis in cardiovascular health”.

All Publications / Bowman Publications

Spatial and temporal alterations in protein structure by EGF regulate cryptic cysteine oxidation

Jessica B. Behring, Sjoerd van der Post, Arshag D. Mooradian, Matthew J. Egan, Maxwell I. Zimmerman, Jenna L. Clements, Gregory R. Bowman, & Jason M. Held (2021). “Spatial and temporal alterations in protein structure by EGF regulate cryptic cysteine oxidation” Sci Signal. 2020 Jan 21;13(615):eaay7315. doi: 10.1126/scisignal.aay7315. (Abstract)

All Publications / Barnes Publications

A Single Amino Acid Change to Taq DNA Polymerase Enables Faster PCR, Reverse Transcription and Strand-Displacement

Wayne M. Barnes, Zhian Zhang, & Milko B. Kermekchiev (2021). “A Single Amino Acid Change to Taq DNA Polymerase Enables Faster PCR, Reverse Transcription and Strand-Displacement” Front. Bioeng. Biotechnol., 14 January 2021, doi: 10.3389/fbioe.2020.553474 (Abstract)

All Publications / Janetka Publications

An Integrated Approach to Identify New Anti-Filarial Leads to Treat River Blindness, a Neglected Tropical Disease

Rahul Tyagi, Christina A. Bulman, Fidelis Cho-Ngwa, Chelsea Fischer, Chris Marcellino, Michelle R. Arkin, James H. McKerrow, Case W. McNamara, Matthew Mahoney, Nancy Tricoche, Shabnam Jawahar, James W. Janetka, Sara Lustigman, Judy Sakanari, & Makedonka Mitreva (2021). “An Integrated Approach to Identify New Anti-Filarial Leads to Treat River Blindness, a Neglected Tropical Disease” Pathogens. 2021 Jan 14;10(1):71. doi: 10.3390/pathogens10010071. (Abstract)

2021 News / All News

2020 John E. Majors Award Recipients

The 2020 John E. Majors Award goes to two individuals – Sarah Clippinger and Emma Winkler.

Ms. Sarah Clippinger was nominated by her advisor, Dr. Michael Greenberg. Ms. Clippinger is a graduate student in the Biochemistry, Biophysics, and Structural Biology Program. She is completing her thesis work on the study of mutations in the protein troponin T that lead to familial cardiomyopathies.

Ms. Emma Winkler was nominated by her advisor, Dr. Michael Diamond. Ms. Winkler is an MSTP student in the Immunology program. She is completing her thesis work on understanding how the intestinal microbiome modulates systemic immune responses to virus infection, specifically mosquito-born alphaviruses such as Chikungunya virus. (more…)